iPTMnet Report for P46977 (STT3A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P46977 / STT3A_HUMAN
Protein Name Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A
Gene Name Name: STT3A
Synonyms:ITM1,TMC;
Organism Homo sapiens (Human)

PRO ID PR:P46977
DAG View
PRO Name dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (human)
Definition A dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A that is encoded in the genome of human.
Short Label hSTT3A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P46977 (STT3A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K3 Ubiquitination PhosphoSitePlus
R8 Methylation PhosphoSitePlus
K13 Ubiquitination PhosphoSitePlus
Y66 Phosphorylation PhosphoSitePlus
K67 Sumoylation PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
S124 O-Glycosylation GlyGen 34846842, 34725712, 30059200, ...29351928, 34019948, 35083852, 32119511, 35254053
K139 Ubiquitination PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
C193 Methylation IEDB 31844290
C198 Methylation IEDB 31844290
C241 Methylation IEDB 31844290
K289 Ubiquitination PhosphoSitePlus
K340 Ubiquitination PhosphoSitePlus
Y392 Phosphorylation PhosphoSitePlus
Y398 Phosphorylation PhosphoSitePlus
K440 Ubiquitination PhosphoSitePlus
K441 Ubiquitination PhosphoSitePlus
K444 Ubiquitination PhosphoSitePlus
Y509 Phosphorylation PhosphoSitePlus
Y510 Phosphorylation PhosphoSitePlus
N537 N-Glycosylation GlyGen   UniProt 29741879, 19159218, 24190977
T539 O-Glycosylation GlyGen 34846842, 34725712, 30059200, ...29351928, 34019948, 35083852, 32119511, 35254053
N544 N-Glycosylation GlyGen   UniProt 29741879, 19159218, 24190977
N545 N-Glycosylation GlyGen 24190977
T546 O-Glycosylation GlyGen 34846842, 34725712, 30059200, ...29351928, 34019948, 35083852, 32119511, 35254053
N548 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
N549 N-Glycosylation GlyGen 24190977
T550 O-Glycosylation GlyGen 34846842, 34725712, 30059200, ...29351928, 34019948, 35083852, 32119511, 35254053
S553 O-Glycosylation GlyGen 34846842, 34725712, 30059200, ...29351928, 34019948, 35083852, 32119511, 35254053
K565 Ubiquitination PhosphoSitePlus
K610 Ubiquitination PhosphoSitePlus
K613 Ubiquitination PhosphoSitePlus
Y617 Phosphorylation PhosphoSitePlus
Y618 Phosphorylation PhosphoSitePlus
T619 Phosphorylation PhosphoSitePlus
T621 Phosphorylation PhosphoSitePlus
C637 Methylation IEDB 31844290
K641 Ubiquitination PhosphoSitePlus
Y651 Phosphorylation PhosphoSitePlus
T652 Phosphorylation PhosphoSitePlus
K655 Ubiquitination PhosphoSitePlus
K671 Ubiquitination PhosphoSitePlus
K695 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N537 N-Glycosylation PRO 29741879


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R8 * Biomuta DOID:363 / uterine cancer [ cosmic ]
Y66 H66 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K340 T340 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
N537 D537 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
T539 A539 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
T550 A550 Biomuta DOID:4606 / bile duct cancer [ cosmic ]