iPTMnet Report for P43694 (GATA4)
Protein Information
UniProt AC / UniProt ID | P43694 / GATA4_HUMAN |
Protein Name | Transcription factor GATA-4 |
Gene Name | Name: GATA4 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P43694 |
PRO Name | transcription factor GATA-4 (human) |
Definition | A transcription factor GATA-4 that is encoded in the genome of human. |
Short Label | hGATA4 |
Category | organism-gene |
P43694 (GATA4) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S105 | Phosphorylation | P28482 (MAPK1) , P27361 (MAPK3) , P11802 (CDK4) | score4 | neXtProt PhosphoSitePlus RLIMS-P+ RLIMS-P | 19546173, 22227582, 21447557, ... | |
S109 | Phosphorylation | score1 | PhosphoSitePlus | |||
S133 | O-Glycosylation | score1 | GlyGen | 30620550 | ||
Y236 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y244 | Phosphorylation | score1 | PhosphoSitePlus | |||
K256 | Ubiquitination | score1 | PhosphoSitePlus | |||
S262 | Phosphorylation | P17612 (PRKACA) | score4 | neXtProt phospho.ELM PhosphoSitePlus | 11719519, 12670947, 16109788 | |
S264 | Phosphorylation | score1 | PhosphoSitePlus | |||
K327 | Acetylation | score1 | PhosphoSitePlus | |||
K329 | Acetylation | score1 | PhosphoSitePlus | |||
S395 | Phosphorylation | score1 | PhosphoSitePlus | |||
S401 | Phosphorylation | score1 | PhosphoSitePlus | |||
S406 | Phosphorylation | score1 | PhosphoSitePlus | |||
S412 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S401 | L401 | Biomuta | DOID:1319 / brain cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic ] |