iPTMnet Report for P43487 (RANBP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P43487 / RANG_HUMAN
Protein Name Ran-specific GTPase-activating protein
Gene Name Name: RANBP1
Organism Homo sapiens (Human)

PRO ID PR:P43487
DAG View
PRO Name Ran-specific GTPase-activating protein (human)
Definition A Ran-specific GTPase-activating protein that is encoded in the genome of human.
Short Label hRANBP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P43487 (RANBP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
K5 Acetylation PhosphoSitePlus
T7 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T13 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17287340
S14 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17287340
T15 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17287340
T18 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17287340
S21 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17287340
S32 Phosphorylation PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
K50 Ubiquitination PhosphoSitePlus
K54 Acetylation PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 24275569
K68 Acetylation PhosphoSitePlus
K68 Methylation PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
K79 Acetylation PhosphoSitePlus
Y103 Phosphorylation PhosphoSitePlus
T105 Phosphorylation PhosphoSitePlus
K111 Acetylation PhosphoSitePlus
K111 Ubiquitination PhosphoSitePlus
T124 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...34725712, 34019948, 21740066, 35132862, 20305658, 32119511, 28510447
C132 Methylation IEDB 31844290
K134 Acetylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
K150 Acetylation PhosphoSitePlus   UniProt 19608861
K150 Ubiquitination PhosphoSitePlus
K152 Acetylation PhosphoSitePlus
K154 Acetylation PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
K160 Acetylation PhosphoSitePlus
K183 Acetylation PhosphoSitePlus   UniProt 19608861
K183 Ubiquitination PhosphoSitePlus
S188 Phosphorylation PhosphoSitePlus   UniProt 23186163
K190 Acetylation PhosphoSitePlus
K190 Sumoylation PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
T193 Phosphorylation PhosphoSitePlus
K194 Acetylation PhosphoSitePlus
K200 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T7 Phosphorylation HPRD 18669648, 17287340, 17081983, ...20068231
T13 Phosphorylation HPRD 18669648, 20068231, 18452278
S14 Phosphorylation HPRD 18669648, 18491316, 17287340, ...20068231, 18452278
T15 Phosphorylation HPRD 18669648, 17287340, 18452278
T18 Phosphorylation HPRD 18669648, 17287340, 20068231, ...18452278
S21 Phosphorylation HPRD 18669648, 17287340, 17081983, ...20068231
S32 Phosphorylation HPRD 17081983
S60 Phosphorylation HPRD 19413330, 20230923, 20058876, ...19664994, 19651622, 20166139
T193 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K5 R5 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S32 Y32 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T193 N193 Biomuta DOID:5041 / esophageal cancer [ cosmic ]