iPTMnet Report for P43003 (SLC1A3)
Protein Information
UniProt AC / UniProt ID | P43003 / EAA1_HUMAN |
Protein Name | Excitatory amino acid transporter 1 |
Gene Name | Name: SLC1A3 Synonyms:EAAT1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P43003 |
PRO Name | excitatory amino acid transporter 1 (human) |
Definition | An excitatory amino acid transporter 1 that is encoded in the genome of human. |
Short Label | hSLC1A3 |
Category | organism-gene |
P43003 (SLC1A3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T2 | Phosphorylation | score1 | PhosphoSitePlus | |||
K3 | Ubiquitination | score1 | PhosphoSitePlus | |||
S4 | Phosphorylation | score1 | PhosphoSitePlus | |||
K10 | Ubiquitination | score1 | PhosphoSitePlus | |||
T26 | Phosphorylation | score1 | PhosphoSitePlus | |||
K31 | Ubiquitination | score1 | PhosphoSitePlus | |||
K32 | Ubiquitination | score1 | PhosphoSitePlus | |||
T37 | Phosphorylation | score1 | PhosphoSitePlus | |||
K38 | Acetylation | score1 | PhosphoSitePlus | |||
K38 | Ubiquitination | score1 | PhosphoSitePlus | |||
S82 | Phosphorylation | score1 | PhosphoSitePlus | |||
K191 | Ubiquitination | score1 | PhosphoSitePlus | |||
K384 | Ubiquitination | score1 | PhosphoSitePlus | |||
S512 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
K520 | Ubiquitination | score1 | PhosphoSitePlus | |||
K521 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y523 | Phosphorylation | score1 | PhosphoSitePlus | |||
K534 | Ubiquitination | score1 | PhosphoSitePlus | |||
K541 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K31 | N31 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:9253 / gastrointestinal stromal tumor [ cosmic ] | |
T37 | A37 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |