iPTMnet Report for P42081 (CD86)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P42081 / CD86_HUMAN
Protein Name T-lymphocyte activation antigen CD86 precursor
Gene Name Name: CD86
Synonyms:CD28LG2;
Organism Homo sapiens (Human)

PRO ID PR:P42081
DAG View
PRO Name T-lymphocyte activation antigen CD86 (human)
Definition A CD86 molecule that is encoded in the genome of human.
Short Label hCD86
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P42081 (CD86) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S77 Phosphorylation PhosphoSitePlus
S80 Phosphorylation PhosphoSitePlus
Y108 Phosphorylation PhosphoSitePlus
T175 Phosphorylation PhosphoSitePlus
N177 N-Glycosylation GlyGen 24190977
K315 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S223 Phosphorylation PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus
T230 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T175 N175 Biomuta DOID:3571 / liver cancer [ cosmic ]
S223 C223 Biomuta DOID:4159 / skin cancer [ cosmic ]
T230 A230 Biomuta DOID:1612 / breast cancer [ cosmic ]
K315 E315 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]