iPTMnet Report for P41567 (EIF1)
Protein Information
UniProt AC / UniProt ID | P41567 / EIF1_HUMAN |
Protein Name | Eukaryotic translation initiation factor 1 |
Gene Name | Name: EIF1 Synonyms:SUI1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P41567 |
PRO Name | eukaryotic translation initiation factor 1 (human) |
Definition | A eukaryotic translation initiation factor 1 that is encoded in the genome of human. |
Short Label | hEIF1 |
Category | organism-gene |
P41567 (EIF1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Acetylation | score1 | UniProt | 19413330, 21406692, 20068231 | ||
S2 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 23186163, 20068231 | ||
S9 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 23186163 | ||
K18 | Ubiquitination | score1 | PhosphoSitePlus | |||
T27 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y30 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 15592455 | ||
K42 | Ubiquitination | score1 | PhosphoSitePlus | |||
T43 | Phosphorylation | score1 | PhosphoSitePlus | |||
T45 | Phosphorylation | score0 | HPRD | 20068231 | ||
Y54 | Phosphorylation | score0 | HPRD | 20068231 | ||
K56 | Methylation | score1 | PhosphoSitePlus | |||
K58 | Acetylation | score1 | PhosphoSitePlus | |||
K61 | Acetylation | score1 | PhosphoSitePlus | |||
K66 | Ubiquitination | score1 | PhosphoSitePlus | |||
C69 | S-Nitrosylation | score0 | dbSNO | 22178444, 19366988, 18335467 | ||
T72 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y79 | Phosphorylation | score1 | PhosphoSitePlus | |||
K91 | Ubiquitination | score1 | PhosphoSitePlus | |||
C94 | Methylation | score1 | IEDB | 31844290 | ||
K109 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S9 | C9 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
K18 | N18 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K56 | E56 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
K61 | T61 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] |