iPTMnet Report for P41221 (WNT5A)
Protein Information
UniProt AC / UniProt ID | P41221 / WNT5A_HUMAN |
Protein Name | Protein Wnt-5a precursor |
Gene Name | Name: WNT5A |
Organism | Homo sapiens (Human) |
PRO ID | PR:P41221 |
PRO Name | protein Wnt-5a (human) |
Definition | A protein Wnt-5a that is encoded in the genome of human. |
Short Label | hWNT5A |
Category | organism-gene |
P41221 (WNT5A) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y86 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y92 | Phosphorylation | score1 | PhosphoSitePlus | |||
T99 | Phosphorylation | score1 | PhosphoSitePlus | |||
N114 | N-Glycosylation | score3 | GlyGen | 23090970, 29741879, 17117926, ... | ||
S116 | Phosphorylation | score1 | PhosphoSitePlus | |||
T117 | Phosphorylation | score1 | PhosphoSitePlus | |||
N120 | N-Glycosylation | score3 | GlyGen | 17117926, 24190977 | ||
T121 | Phosphorylation | score1 | PhosphoSitePlus | |||
S122 | Phosphorylation | score1 | PhosphoSitePlus | |||
K194 | Ubiquitination | score1 | PhosphoSitePlus | |||
K208 | Ubiquitination | score1 | PhosphoSitePlus | |||
K261 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y270 | Phosphorylation | score1 | PhosphoSitePlus | |||
S272 | Phosphorylation | score1 | PhosphoSitePlus | |||
S280 | Phosphorylation | score1 | PhosphoSitePlus | |||
K283 | Ubiquitination | score1 | PhosphoSitePlus | |||
K348 | Ubiquitination | score1 | PhosphoSitePlus | |||
C379 | Methylation | score1 | IEDB | 31844290 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y86 | D86 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
T99 | S99 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S116 | N116 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S122 | Y122 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
K261 | E261 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
Y270 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
K283 | R283 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] |