iPTMnet Report for P41182 (BCL6)
Protein Information
UniProt AC / UniProt ID | P41182 / BCL6_HUMAN |
Protein Name | B-cell lymphoma 6 protein |
Gene Name | Name: BCL6 Synonyms:BCL5,LAZ3,ZBTB27,ZNF51; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P41182 |
PRO Name | B-cell lymphoma 6 protein (human) |
Definition | A B-cell lymphoma 6 protein that is encoded in the genome of human. |
Short Label | hBCL6 |
Category | organism-gene |
P41182 (BCL6) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y157 | Phosphorylation | score1 | PhosphoSitePlus | |||
S256 | Phosphorylation | score1 | PhosphoSitePlus | |||
S260 | Phosphorylation | score1 | PhosphoSitePlus | |||
K282 | Ubiquitination | score1 | PhosphoSitePlus | |||
K298 | Ubiquitination | score1 | PhosphoSitePlus | |||
R305 | Methylation | score1 | PhosphoSitePlus | |||
S307 | Phosphorylation | score1 | PhosphoSitePlus | |||
S308 | Phosphorylation | score1 | PhosphoSitePlus | |||
S330 | Phosphorylation | score1 | PhosphoSitePlus | |||
S333 | Phosphorylation | P28482 (MAPK1) , P27361 (MAPK3) | score4 | neXtProt PhosphoSitePlus Signor UniProt | 9649500, 23186163 | |
S337 | Phosphorylation | score1 | PhosphoSitePlus | |||
S343 | Phosphorylation | P27361 (MAPK3) , P28482 (MAPK1) | score3 | neXtProt PhosphoSitePlus Signor UniProt | 9649500 | |
S359 | Phosphorylation | score1 | PhosphoSitePlus | |||
S361 | Phosphorylation | score1 | PhosphoSitePlus | |||
K371 | Ubiquitination | score1 | PhosphoSitePlus | |||
K379 | Acetylation | score3 | PhosphoSitePlus UniProt | 12402037 | ||
S385 | Phosphorylation | score1 | PhosphoSitePlus | |||
S404 | Phosphorylation | score1 | PhosphoSitePlus | |||
S427 | Phosphorylation | score1 | PhosphoSitePlus | |||
S466 | Phosphorylation | score1 | PhosphoSitePlus | |||
T569 | Phosphorylation | score1 | PhosphoSitePlus | |||
K572 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y574 | Phosphorylation | score1 | PhosphoSitePlus | |||
S597 | Phosphorylation | score1 | PhosphoSitePlus | |||
T625 | Phosphorylation | score1 | PhosphoSitePlus | |||
T653 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S3 | L3 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ] | |
S260 | L260 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
R305 | I305 | Biomuta | DOID:184 / bone cancer [ cosmic ] | |
S330 | C330 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S359 | F359 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S361 | F361 | Biomuta | DOID:4362 / cervical cancer [ cosmic ] | |
S404 | F404 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S597 | C597 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
T625 | S625 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |