iPTMnet Report for P40429 (RPL13A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P40429 / RL13A_HUMAN
Protein Name Large ribosomal subunit protein uL13
Gene Name Name: RPL13A
Organism Homo sapiens (Human)

PRO ID PR:P40429
DAG View
PRO Name 60S ribosomal protein L13a (human)
Definition A 60S ribosomal protein L13a that is encoded in the genome of human.
Short Label hRPL13A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P40429 (RPL13A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Phosphorylation PRO
A2 Acetylation PRO   UniProt 19413330, 22223895, 25489052, ...22814378, 12962325, 18995835, 25944712
R12 Methylation PhosphoSitePlus
K25 Acetylation PhosphoSitePlus
K25 Ubiquitination PhosphoSitePlus
C38 S-Nitrosylation dbSNO 26338901
K51 Ubiquitination PhosphoSitePlus
K53 Acetylation PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
R68 Methylation PhosphoSitePlus
R74 Methylation PhosphoSitePlus
S77 Phosphorylation P53355 (DAPK1) , O43293 (DAPK3) , PR:000037784 (hDAPK3/Phos:1) phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 18995835, 12962325, 22771119, ...23071094
K91 Ubiquitination PhosphoSitePlus
R101 Methylation PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
Y112 Phosphorylation IEDB 32387766
K114 Ubiquitination PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
K125 Acetylation PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
K134 Acetylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
Y137 Phosphorylation PhosphoSitePlus
K148 Acetylation PhosphoSitePlus
K148 Methylation PhosphoSitePlus
K148 Ubiquitination PhosphoSitePlus
Y149 Phosphorylation PhosphoSitePlus
T153 Phosphorylation PhosphoSitePlus
T155 Phosphorylation PhosphoSitePlus
K159 Ubiquitination PhosphoSitePlus
K163 Acetylation PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
K191 Acetylation PhosphoSitePlus   UniProt 19608861
K191 Ubiquitination PhosphoSitePlus
T193 Phosphorylation HPRD 20068231
K197 Acetylation PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000037783 (hRPL13A/InitMet-/AcPhos:1) acA2 PRO 12962325, 18995835
PR:000037783 (hRPL13A/InitMet-/AcPhos:1) pS77 PR:000037784 (hDAPK3/Phos:1) PRO 12962325, 18995835
PR:000049071 (hRPL13A/InitMet-/PhosRes+) p PRO


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P40429 (RPL13A) S77 P04406 (GAPDH) unknown eFIP 29152905


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 E2 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
R12 Q12 Biomuta DOID:4159 / skin cancer [ cosmic ]
R68 Q68 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
R101 C101 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K114 E114 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K197 N197 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]