iPTMnet Report for P40222 (TXLNA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P40222 / TXLNA_HUMAN
Protein Name Alpha-taxilin
Gene Name Name: TXLNA
Synonyms:TXLN;
Organism Homo sapiens (Human)

PRO ID PR:P40222
DAG View
PRO Name alpha-taxilin (human)
Definition An alpha-taxilin that is encoded in the genome of human.
Short Label hTXLNA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P40222 (TXLNA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S18 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18691976, 18220336, 18452278, ...18669648, 20068231
S19 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19413330, 17287340, 18220336, ...18452278, 18669648
S35 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
K54 Ubiquitination PhosphoSitePlus
R69 Methylation PhosphoSitePlus
S72 Phosphorylation PhosphoSitePlus   UniProt 23186163
S113 Phosphorylation IEDB   PhosphoSitePlus 27920218
R146 Methylation PhosphoSitePlus
S148 Phosphorylation PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus
C193 Methylation IEDB 31844290
K194 Acetylation PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
K195 Acetylation PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
S218 Phosphorylation PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
S232 Phosphorylation PhosphoSitePlus
K233 Ubiquitination PhosphoSitePlus
K240 Acetylation PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
S243 Phosphorylation PhosphoSitePlus
S254 Phosphorylation PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
R308 Methylation PhosphoSitePlus
K311 Acetylation PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
K330 Ubiquitination PhosphoSitePlus
K340 Ubiquitination PhosphoSitePlus
K364 Ubiquitination PhosphoSitePlus
K377 Ubiquitination PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
K403 Ubiquitination PhosphoSitePlus
K412 Ubiquitination PhosphoSitePlus
T419 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
K421 Acetylation PhosphoSitePlus
K427 Ubiquitination PhosphoSitePlus
K441 Ubiquitination PhosphoSitePlus
K455 Ubiquitination PhosphoSitePlus
K463 Ubiquitination PhosphoSitePlus
S489 Phosphorylation HPRD   PhosphoSitePlus 18452278
S495 Phosphorylation HPRD   PhosphoSitePlus 20068231
T497 Phosphorylation PhosphoSitePlus
S499 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S514 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18691976, 17081983, 19664995, ...19651622, 18669648, 20166139, 20068231
S515 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17322306, 21406692, 23186163, ...18767875, 19664995, 18452278, 19651622, 18669648, 19415658, 24275569, 20166139, 17287340, 19690332, 20068231, 20068230
T519 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...31492838, 35254053, 35132862, 32119511, 34229054
T519 Phosphorylation PhosphoSitePlus
C523 S-Nitrosylation dbSNO 26338901
Y524 Phosphorylation PhosphoSitePlus
S529 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...31492838, 35254053, 35132862, 32119511, 34229054
S543 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R69 C69 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4362 / cervical cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
K377 E377 Biomuta DOID:1324 / lung cancer [ cosmic ]
K393 N393 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K427 R427 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S495 F495 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]