iPTMnet Report for P40145 (ADCY8)
Protein Information
| UniProt AC / UniProt ID | P40145 / ADCY8_HUMAN |
| Protein Name | Adenylate cyclase type 8 |
| Gene Name | Name: ADCY8 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P40145 |
| PRO Name | adenylate cyclase type 8 (human) |
| Definition | An adenylate cyclase type 8 that is encoded in the genome of human. |
| Short Label | hADCY8 |
| Category | organism-gene |
DAG ViewP40145 (ADCY8) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S4 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T500 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y764 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1154 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1159 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18669648 | ||
| T1245 | Phosphorylation | score1 | PhosphoSitePlus |
PTM-dependent PPI
|
PTM type | Substrate | Site | Interactant | Association type | Source | PMID |
|---|---|---|---|---|---|---|---|
| Phosphorylation | Q96D31 (ORAI1) | S30 | P40145 (ADCY8) | unknown | eFIP | 31652779 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S4 | F4 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S1159 | G1159 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S1159 | N1159 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
