iPTMnet Report for P39905 (GDNF)
Protein Information
UniProt AC / UniProt ID | P39905 / GDNF_HUMAN |
Protein Name | Glial cell line-derived neurotrophic factor precursor |
Gene Name | Name: GDNF |
Organism | Homo sapiens (Human) |
PRO ID | PR:P39905 |
PRO Name | glial cell line-derived neurotrophic factor (human) |
Definition | A glial cell line-derived neurotrophic factor that is encoded in the genome of human. |
Short Label | hGDNF |
Category | organism-gene |
P39905 (GDNF) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
N126 | N-Glycosylation | score3 | GlyGen UniProt | 19478429 | ||
S146 | Phosphorylation | score1 | PhosphoSitePlus | |||
S148 | Phosphorylation | score1 | PhosphoSitePlus | |||
T154 | Phosphorylation | score1 | PhosphoSitePlus | |||
T155 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y156 | Phosphorylation | score1 | PhosphoSitePlus | |||
S164 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T154 | I154 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
T155 | M155 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] DOID:363 / uterine cancer [ icgc ] DOID:1324 / lung cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
Y156 | H156 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S164 | F164 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S164 | C164 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |