iPTMnet Report for P37108 (SRP14)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P37108 / SRP14_HUMAN
Protein Name Signal recognition particle 14 kDa protein
Gene Name Name: SRP14
Organism Homo sapiens (Human)

PRO ID PR:P37108
DAG View
PRO Name signal recognition particle 14 kDa protein (human)
Definition A signal recognition particle 14 kDa protein that is encoded in the genome of human.
Short Label hSRP14
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P37108 (SRP14) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S25 Phosphorylation PhosphoSitePlus
Y27 Phosphorylation PhosphoSitePlus   UniProt 24275569
T29 Phosphorylation PhosphoSitePlus
Y33 Phosphorylation PhosphoSitePlus
T37 Phosphorylation PhosphoSitePlus
K43 Ubiquitination PhosphoSitePlus
T45 Phosphorylation PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
K64 Ubiquitination PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
K74 Ubiquitination PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
S84 Phosphorylation PhosphoSitePlus
K95 Ubiquitination PhosphoSitePlus
K105 Methylation PhosphoSitePlus
T106 Phosphorylation PhosphoSitePlus
K107 Methylation PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
T122 O-Glycosylation GlyGen 27114449, 28510447, 35138101, ...30379171, 34725712, 33214551, 21740066, 35254053, 34019948, 32119511, 36580660, 35289036, 30620550, 34229054
T125 O-Glycosylation GlyGen 31373491
T126 O-Glycosylation GlyGen 27114449, 28510447, 35138101, ...30379171, 34725712, 33214551, 21740066, 35254053, 34019948, 31373491, 32119511, 36580660, 35289036, 30620550, 34229054
T129 O-Glycosylation GlyGen 31373491
T133 O-Glycosylation GlyGen 27114449, 28510447, 35138101, ...30379171, 34725712, 33214551, 21740066, 35254053, 34019948, 32119511, 36580660, 35289036, 30620550, 34229054


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K66 T66 Biomuta DOID:363 / uterine cancer [ icgc ]
K78 T78 Biomuta DOID:363 / uterine cancer [ icgc ]
K95 N95 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K105 N105 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T125 A125 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
T126 A126 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T129 A129 Biomuta DOID:5041 / esophageal cancer [ cosmic ]