Protein Information

Cytoscape View


UniProt AC / UniProt ID P37059 / DHB2_HUMAN
Protein Name 17-beta-hydroxysteroid dehydrogenase type 2
Gene Name Name: HSD17B2
Synonyms:EDH17B2,SDR9C2;
Organism Homo sapiens (Human)

PRO ID PR:P37059
DAG View
PRO Name 17-beta-hydroxysteroid dehydrogenase type 2 (human)
Definition A 17-beta-hydroxysteroid dehydrogenase type 2 that is encoded in the genome of human.
Short Label hHSD17B2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P37059 (HSD17B2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K141 Acetylation PhosphoSitePlus
S251 Phosphorylation PhosphoSitePlus
S259 Phosphorylation PhosphoSitePlus
T267 Phosphorylation PhosphoSitePlus
S273 Phosphorylation HPRD 17081983
Y353 Phosphorylation PhosphoSitePlus
Y361 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S251 F251 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y353 * Biomuta DOID:2394 / ovarian cancer [ cosmic ]