iPTMnet Report for P36957 (DLST)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P36957 / ODO2_HUMAN
Protein Name Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial precursor
Gene Name Name: DLST
Synonyms:DLTS;
Organism Homo sapiens (Human)

PRO ID PR:P36957
DAG View
PRO Name dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (human)
Definition A dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial that is encoded in the genome of human.
Short Label hDLST
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P36957 (DLST) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 O-Glycosylation GlyGen 30379171, 34725712, 34229054, ...35008409
S5 O-Glycosylation GlyGen 30379171, 34725712, 34229054, ...35008409
K74 Ubiquitination PhosphoSitePlus
S81 Phosphorylation PhosphoSitePlus
T83 Phosphorylation PhosphoSitePlus
T138 Phosphorylation PhosphoSitePlus
K203 Ubiquitination PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
K267 Acetylation PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
K272 Acetylation PhosphoSitePlus
K273 Acetylation PhosphoSitePlus
K277 Acetylation PhosphoSitePlus
K277 Ubiquitination PhosphoSitePlus
S282 Phosphorylation PhosphoSitePlus
K307 Acetylation PhosphoSitePlus
K307 Ubiquitination PhosphoSitePlus
T323 Phosphorylation PhosphoSitePlus
K353 Ubiquitination PhosphoSitePlus
R437 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S221 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S3 F3 Biomuta DOID:363 / uterine cancer [ cosmic ]
S81 F81 Biomuta DOID:4159 / skin cancer [ cosmic ]
T323 A323 Biomuta DOID:1319 / brain cancer [ cosmic ]
R437 C437 Biomuta DOID:4159 / skin cancer [ cosmic ]
R437 H437 Biomuta DOID:9256 / colorectal cancer [ cosmic ]