Protein Information

Cytoscape View


UniProt AC / UniProt ID P36955 / PEDF_HUMAN
Protein Name Pigment epithelium-derived factor precursor
Gene Name Name: SERPINF1
Synonyms:PEDF;ORFNames:PIG35;
Organism Homo sapiens (Human)

PRO ID PR:P36955
DAG View
PRO Name pigment epithelium-derived factor (human)
Definition A pigment epithelium-derived factor that is encoded in the genome of human.
Short Label hSERPINF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P36955 (SERPINF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S24 O-Glycosylation GlyGen 30459171
S24 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 15374885
S24 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus 15374885
S30 O-Glycosylation GlyGen 30459171
T36 O-Glycosylation GlyGen 30459171
S114 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 15374885
S114 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus 15374885
S152 Phosphorylation PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
T170 Phosphorylation IEDB 35494241
S227 Phosphorylation PhosphoSitePlus   UniProt 15374885
S227 Phosphorylation P17612 (PRKACA) PhosphoSitePlus 15374885
T283 Phosphorylation PhosphoSitePlus
N285 N-Glycosylation GlyGen   UniProt 16335952, 19159218, 29391424, ...19139490, 24279413, 11562499, 29741879
T287 Phosphorylation PhosphoSitePlus
T294 Phosphorylation PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus
K316 Methylation PhosphoSitePlus
T372 O-Glycosylation GlyGen 30459171
S374 O-Glycosylation GlyGen 30459171


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S114 N114 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4362 / cervical cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S152 T152 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S152 F152 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S153 R153 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]