iPTMnet Report for P36542 (ATP5F1C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P36542 / ATPG_HUMAN
Protein Name ATP synthase subunit gamma, mitochondrial precursor
Gene Name Name: ATP5F1C
Synonyms:ATP5C;
Organism Homo sapiens (Human)

PRO ID PR:P36542
DAG View
PRO Name ATP synthase subunit gamma, mitochondrial (human)
Definition An ATP synthase subunit gamma, mitochondrial that is encoded in the genome of human.
Short Label hATP5F1C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P36542 (ATP5F1C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R33 Methylation PhosphoSitePlus
K39 Acetylation PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
K43 Acetylation PhosphoSitePlus
K43 Ubiquitination PhosphoSitePlus
T45 Phosphorylation PhosphoSitePlus
K49 Acetylation PhosphoSitePlus
K49 Ubiquitination PhosphoSitePlus
K55 Acetylation PhosphoSitePlus   UniProt 19608861
K55 Ubiquitination PhosphoSitePlus
S73 Phosphorylation PhosphoSitePlus
K79 Acetylation PhosphoSitePlus
K88 Acetylation PhosphoSitePlus
K89 Acetylation PhosphoSitePlus
K90 Acetylation PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus
R100 Methylation PhosphoSitePlus
S108 Phosphorylation PhosphoSitePlus
S109 Phosphorylation PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus
T122 Phosphorylation PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
T144 Phosphorylation PhosphoSitePlus
S146 Phosphorylation P17252 (PRKCA) PhosphoSitePlus   UniProt 25627689, 23186163
K154 Acetylation PhosphoSitePlus   UniProt 19608861
K189 Acetylation PhosphoSitePlus
K197 Acetylation PhosphoSitePlus   UniProt 19608861
K197 Ubiquitination PhosphoSitePlus
K262 Ubiquitination PhosphoSitePlus
S265 Phosphorylation PhosphoSitePlus
K270 Ubiquitination PhosphoSitePlus
T284 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T45 Phosphorylation HPRD 20068231
S116 Phosphorylation HPRD 20068231
T122 Phosphorylation HPRD 20068231
S146 Phosphorylation HPRD 19651622
Site PTM Type PTM Enzyme Score Source PMID
T45 Phosphorylation HPRD 20068231
S116 Phosphorylation HPRD 20068231
T122 Phosphorylation HPRD 20068231
S146 Phosphorylation HPRD 19651622


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K39 R39 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S97 F97 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
R100 L100 Biomuta DOID:3571 / liver cancer [ cosmic ]
S108 F108 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S146 Y146 Biomuta DOID:4159 / skin cancer [ cosmic ]
K189 * Biomuta DOID:263 / kidney cancer [ cosmic ]
K270 R270 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T284 K284 Biomuta [ cosmic ]