Protein Information

Cytoscape View


UniProt AC / UniProt ID P36406 / TRI23_HUMAN
Protein Name E3 ubiquitin-protein ligase TRIM23
Gene Name Name: TRIM23
Synonyms:ARD1,ARFD1,RNF46;
Organism Homo sapiens (Human)

PRO ID PR:P36406
DAG View
PRO Name E3 ubiquitin-protein ligase TRIM23 (human)
Definition An E3 ubiquitin-protein ligase TRIM23 that is encoded in the genome of human.
Short Label hTRIM23
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P36406 (TRIM23) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K8 Ubiquitination PhosphoSitePlus
S15 Phosphorylation PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
K357 Ubiquitination PhosphoSitePlus
S386 Phosphorylation PhosphoSitePlus
K458 Acetylation PhosphoSitePlus
Y468 Phosphorylation PhosphoSitePlus
Y469 Phosphorylation PhosphoSitePlus
K501 Ubiquitination PhosphoSitePlus
S550 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K8 R8 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S15 C15 Biomuta DOID:3571 / liver cancer [ cosmic ]
S386 N386 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
K458 N458 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y469 H469 Biomuta DOID:5158 / pleural cancer [ cosmic ]