iPTMnet Report for P35732 (DEF1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P35732 / DEF1_YEAST
Protein Name RNA polymerase II degradation factor 1
Gene Name Name: DEF1
Synonyms:RIP1,VID31;OrderedLocusNames:YKL054C;ORFNames:YKL308;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

PRO ID PR:P35732
DAG View
PRO Name RNA polymerase II degradation factor 1 (yeast)
Definition A protein that is a translation product of the DEF1 gene in yeast.
Short Label yDEF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P35732 (DEF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S104 Phosphorylation SGD 33481703
S108 Phosphorylation SGD 32597660, 23749301, 18407956, ...33481703
S110 Phosphorylation SGD 33481703, 32597660, 33491328, ...18407956, 23749301
T112 Phosphorylation BioGRID 21177495
K115 Ubiquitination SGD 23749301
S118 Phosphorylation SGD 33491328, 18407956
S119 Phosphorylation SGD 32597660
T133 Phosphorylation SGD 32597660
K147 Ubiquitination SGD 23749301
S178 Phosphorylation SGD 33491328
S224 Phosphorylation BioGRID   SGD 21126336, 33481703
S226 Phosphorylation SGD 32597660, 33481703
S227 Phosphorylation SGD 33481703, 33491328
S235 Phosphorylation SGD 32597660, 33491328
S243 Phosphorylation BioGRID   SGD 19779198, 33481703, 33491328, ...23749301
T249 Phosphorylation SGD 23749301, 33481703
T258 Phosphorylation BioGRID   SGD 19795423, 33481703, 20702584, ...23749301, 27821475, 21126336, 33491328, 19823750
S260 Phosphorylation BioGRID   SGD   UniProt 19795423, 33481703, 17563356, ...17330950, 24909858, 21177495, 20702584, 18407956, 23749301, 22218487, 19779198, 27821475, 19684113, 17287358, 32597660, 33491328, 19823750
K269 Sumoylation SGD 33502312
K270 Sumoylation SGD 33502312
S273 Phosphorylation BioGRID   SGD   UniProt 19795423, 33481703, 17563356, ...17287358, 32597660, 33491328
S282 Phosphorylation SGD 23749301, 33491328
S307 Phosphorylation BioGRID   SGD   UniProt 19779198, 19795423, 33481703, ...19823750
K333 Sumoylation SGD 33502312
T338 Phosphorylation BioGRID   SGD   UniProt 19823750, 19795423, 33481703, ...18407956, 33491328
T357 Phosphorylation SGD 33481703
S494 Phosphorylation BioGRID   SGD 33491328, 18407956
S497 Phosphorylation BioGRID   SGD 18407956
T638 Phosphorylation SGD 32597660, 33491328
S646 Phosphorylation BioGRID   SGD   UniProt 33481703, 17563356, 17330950, ...24909858, 18407956, 23749301, 21177495, 19779198, 19684113, 32597660, 33491328
S658 Phosphorylation SGD 32597660