iPTMnet Report for P35712 (SOX6)
Protein Information
UniProt AC / UniProt ID | P35712 / SOX6_HUMAN |
Protein Name | Transcription factor SOX-6 |
Gene Name | Name: SOX6 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P35712 |
PRO Name | transcription factor SOX-6 (human) |
Definition | A transcription factor SOX-6 that is encoded in the genome of human. |
Short Label | hSOX6 |
Category | organism-gene |
P35712 (SOX6) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S8 | Phosphorylation | score1 | PhosphoSitePlus | |||
T21 | Phosphorylation | score1 | PhosphoSitePlus | |||
T25 | Phosphorylation | score1 | PhosphoSitePlus | |||
C87 | Methylation | score1 | IEDB | 31844290 | ||
S98 | Phosphorylation | score1 | PhosphoSitePlus | |||
S106 | Phosphorylation | score1 | PhosphoSitePlus | |||
T119 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S126 | Phosphorylation | score1 | PhosphoSitePlus | |||
K159 | Ubiquitination | score1 | PhosphoSitePlus | |||
S171 | Phosphorylation | score1 | PhosphoSitePlus | |||
K340 | Ubiquitination | score1 | PhosphoSitePlus | |||
S376 | O-Glycosylation | score1 | GlyGen | 36240223 | ||
S380 | O-Glycosylation | score1 | GlyGen | 36240223 | ||
S380 | Phosphorylation | score1 | PhosphoSitePlus | |||
S399 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K404 | Sumoylation | score1 | PhosphoSitePlus | |||
S411 | Phosphorylation | score1 | PhosphoSitePlus | |||
K417 | Sumoylation | score1 | PhosphoSitePlus | |||
S439 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S442 | Phosphorylation | score1 | PhosphoSitePlus | |||
T444 | Phosphorylation | score1 | PhosphoSitePlus | |||
S454 | Phosphorylation | score1 | PhosphoSitePlus | |||
S466 | Phosphorylation | score1 | PhosphoSitePlus | |||
R474 | Methylation | score1 | PhosphoSitePlus | |||
S476 | Phosphorylation | score1 | PhosphoSitePlus | |||
S477 | Phosphorylation | score1 | PhosphoSitePlus | |||
S486 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y671 | Phosphorylation | score1 | PhosphoSitePlus | |||
S678 | Phosphorylation | score1 | PhosphoSitePlus | |||
T697 | Phosphorylation | score1 | PhosphoSitePlus | |||
S716 | Phosphorylation | score1 | PhosphoSitePlus | |||
T759 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T21 | A21 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S106 | I106 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
S106 | C106 | Biomuta | DOID:5158 / pleural cancer [ cosmic ] | |
S376 | T376 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
S442 | Y442 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
T444 | I444 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S476 | P476 | Biomuta | DOID:5041 / esophageal cancer [ cosmic, icgc ] | |
S678 | R678 | Biomuta | [ cosmic ] | |
T697 | I697 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ] | |
T759 | A759 | Biomuta | DOID:2394 / ovarian cancer [ cosmic ] |