iPTMnet Report for P35606 (COPB2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P35606 / COPB2_HUMAN
Protein Name Coatomer subunit beta'
Gene Name Name: COPB2
Organism Homo sapiens (Human)

PRO ID PR:P35606
DAG View
PRO Name coatomer subunit beta' (human)
Definition A coatomer subunit beta' that is encoded in the genome of human.
Short Label hCOPB2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P35606 (COPB2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S15 Phosphorylation PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus
T26 Phosphorylation PhosphoSitePlus
C56 Methylation IEDB 31844290
K64 Ubiquitination PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
Y86 Phosphorylation PhosphoSitePlus
S99 Phosphorylation PhosphoSitePlus
Y101 Phosphorylation PhosphoSitePlus
C104 Methylation IEDB 31844290
T116 Phosphorylation PhosphoSitePlus
R165 Methylation PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
S176 Phosphorylation PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
K212 Ubiquitination PhosphoSitePlus
C234 Methylation IEDB 31844290
C276 Methylation IEDB 31844290
K318 Acetylation PhosphoSitePlus
K318 Ubiquitination PhosphoSitePlus
K328 Ubiquitination PhosphoSitePlus
K346 Ubiquitination PhosphoSitePlus
S350 Phosphorylation PhosphoSitePlus
Y354 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
K386 Ubiquitination PhosphoSitePlus
S401 Phosphorylation PhosphoSitePlus
Y403 Phosphorylation PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus
S423 O-Glycosylation GlyGen 33214551, 35138101, 34725712, ...29351928, 34019948, 32870666, 29485866, 32119511
K425 Ubiquitination PhosphoSitePlus
S432 O-Glycosylation GlyGen 33214551, 35138101, 34725712, ...29351928, 34019948, 32870666, 29485866, 32119511
T560 Phosphorylation PhosphoSitePlus
S604 Phosphorylation PhosphoSitePlus
K608 Ubiquitination PhosphoSitePlus
T612 Phosphorylation PhosphoSitePlus
K615 Ubiquitination PhosphoSitePlus
K627 Acetylation PhosphoSitePlus   UniProt 19608861
K627 Ubiquitination PhosphoSitePlus
S679 Phosphorylation PhosphoSitePlus
Y696 Phosphorylation PhosphoSitePlus
K724 Ubiquitination PhosphoSitePlus
S731 Phosphorylation PhosphoSitePlus
Y732 Phosphorylation PhosphoSitePlus
S767 Phosphorylation PhosphoSitePlus
K771 Ubiquitination PhosphoSitePlus
K779 Ubiquitination PhosphoSitePlus
K783 Ubiquitination PhosphoSitePlus
S787 Phosphorylation PhosphoSitePlus
Y794 Phosphorylation PhosphoSitePlus
K822 Ubiquitination PhosphoSitePlus
T828 Phosphorylation PhosphoSitePlus
R833 Methylation PhosphoSitePlus
K840 Ubiquitination PhosphoSitePlus
S845 Phosphorylation PhosphoSitePlus
T848 Phosphorylation PhosphoSitePlus
S859 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 24275569, 19690332, 20068231
T861 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S867 Phosphorylation PhosphoSitePlus
T869 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y354 Phosphorylation HPRD 18083107
T612 Phosphorylation HPRD 20068231
S787 Phosphorylation HPRD 20068231
S859 Phosphorylation HPRD 19413330, 18691976, 18491316, ...17081983, 20058876, 19664995, 18452278, 19651622, 18669648, 20166139, 20068231, 17924679
T861 Phosphorylation HPRD 19413330, 20058876, 18452278, ...19651622, 18669648, 20166139, 20068231
S867 Phosphorylation HPRD 20166139
T869 Phosphorylation HPRD 19651622


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T116 A116 Biomuta [ cosmic ]
Y354 C354 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y403 C403 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S423 L423 Biomuta DOID:4159 / skin cancer [ cosmic ]
S423 T423 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
K608 T608 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K627 N627 Biomuta DOID:263 / kidney cancer [ cosmic ]
S767 L767 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K771 T771 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T828 M828 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T861 I861 Biomuta DOID:4362 / cervical cancer [ cosmic ]