Protein Information

Cytoscape View


UniProt AC / UniProt ID P35219 / CAH8_HUMAN
Protein Name Carbonic anhydrase-related protein
Gene Name Name: CA8
Synonyms:CALS;
Organism Homo sapiens (Human)

PRO ID PR:P35219
DAG View
PRO Name carbonic anhydrase-related protein (human)
Definition A carbonic anhydrase-related protein that is encoded in the genome of human.
Short Label hCA8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P35219 (CA8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation HPRD   PhosphoSitePlus 19651622
Y48 Phosphorylation PhosphoSitePlus
S64 Phosphorylation IEDB 35494241
S71 Phosphorylation PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y48 H48 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S64 L64 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S71 F71 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K96 T96 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K258 M258 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]