iPTMnet Report for P34913 (EPHX2)
Protein Information
UniProt AC / UniProt ID | P34913 / HYES_HUMAN |
Protein Name | Bifunctional epoxide hydrolase 2 |
Gene Name | Name: EPHX2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P34913 |
PRO Name | bifunctional epoxide hydrolase 2 (human) |
Definition | An epoxide hydrolase 2 that is encoded in the genome of human. |
Short Label | hEPHX2 |
Category | organism-gene |
P34913 (EPHX2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K43 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K43 | Ubiquitination | score1 | PhosphoSitePlus | |||
K55 | Ubiquitination | score1 | PhosphoSitePlus | |||
K79 | Ubiquitination | score1 | PhosphoSitePlus | |||
K84 | Ubiquitination | score1 | PhosphoSitePlus | |||
K89 | Ubiquitination | score1 | PhosphoSitePlus | |||
K94 | Acetylation | score1 | PhosphoSitePlus | |||
K94 | Ubiquitination | score1 | PhosphoSitePlus | |||
K114 | Acetylation | score1 | PhosphoSitePlus | |||
K115 | Acetylation | score1 | PhosphoSitePlus | |||
K167 | Acetylation | score1 | PhosphoSitePlus | |||
K174 | Acetylation | score1 | PhosphoSitePlus | |||
K174 | Ubiquitination | score1 | PhosphoSitePlus | |||
K191 | Ubiquitination | score1 | PhosphoSitePlus | |||
T243 | Phosphorylation | score1 | IEDB | 35494241 | ||
K245 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y296 | Phosphorylation | score1 | PhosphoSitePlus | |||
S299 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y308 | Phosphorylation | score1 | PhosphoSitePlus | |||
S370 | Phosphorylation | score1 | PhosphoSitePlus | |||
K406 | Ubiquitination | score1 | PhosphoSitePlus | |||
S412 | Phosphorylation | score1 | PhosphoSitePlus | |||
K421 | Ubiquitination | score1 | PhosphoSitePlus | |||
K455 | Acetylation | score1 | PhosphoSitePlus | |||
K474 | Ubiquitination | score1 | PhosphoSitePlus | |||
K478 | Ubiquitination | score1 | PhosphoSitePlus | |||
K483 | Ubiquitination | score1 | PhosphoSitePlus | |||
K515 | Ubiquitination | score1 | PhosphoSitePlus | |||
K530 | Ubiquitination | score1 | PhosphoSitePlus | |||
K540 | Ubiquitination | score1 | PhosphoSitePlus | |||
K554 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K55 | R55 | Biomuta | [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
K79 | E79 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K84 | N84 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K167 | T167 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
K245 | N245 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S299 | L299 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K455 | E455 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K474 | T474 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
K540 | M540 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |