iPTMnet Report for P33402 (GUCY1A2)
Protein Information
UniProt AC / UniProt ID | P33402 / GCYA2_HUMAN |
Protein Name | Guanylate cyclase soluble subunit alpha-2 |
Gene Name | Name: GUCY1A2 Synonyms:GUC1A2,GUCSA2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P33402 |
PRO Name | guanylate cyclase soluble subunit alpha-2 (human) |
Definition | A guanylate cyclase soluble subunit alpha-2 that is encoded in the genome of human. |
Short Label | hGUCY1A2 |
Category | organism-gene |
P33402 (GUCY1A2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S41 | Phosphorylation | score1 | PhosphoSitePlus | |||
S89 | Phosphorylation | score1 | PhosphoSitePlus | |||
S93 | Phosphorylation | score1 | PhosphoSitePlus | |||
T108 | Phosphorylation | score1 | PhosphoSitePlus | |||
K460 | Ubiquitination | score1 | PhosphoSitePlus | |||
K466 | Acetylation | score1 | PhosphoSitePlus | |||
S619 | Phosphorylation | score1 | PhosphoSitePlus | |||
S621 | Phosphorylation | score1 | PhosphoSitePlus | |||
S671 | Phosphorylation | score1 | PhosphoSitePlus | |||
T673 | Phosphorylation | score1 | PhosphoSitePlus | |||
T701 | Phosphorylation | score1 | PhosphoSitePlus | |||
S719 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K466 | E466 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S671 | N671 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S671 | R671 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ] | |
S719 | F719 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |