iPTMnet Report for P32418 (SLC8A1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P32418 / NAC1_HUMAN
Protein Name Sodium/calcium exchanger 1 precursor
Gene Name Name: SLC8A1
Synonyms:CNC,NCX1;
Organism Homo sapiens (Human)

PRO ID PR:P32418
DAG View
PRO Name sodium/calcium exchanger 1 (human)
Definition A sodium/calcium exchanger 1 that is encoded in the genome of human.
Short Label hSLC8A1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P32418 (SLC8A1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S93 Phosphorylation PhosphoSitePlus
T138 Phosphorylation PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
S284 Phosphorylation PhosphoSitePlus
Y351 Phosphorylation PhosphoSitePlus
T369 Phosphorylation PhosphoSitePlus
T373 Phosphorylation PhosphoSitePlus
S392 Phosphorylation PhosphoSitePlus
T437 Phosphorylation PhosphoSitePlus
Y574 Phosphorylation PhosphoSitePlus
S724 Phosphorylation PhosphoSitePlus
T725 Phosphorylation PhosphoSitePlus
S834 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y646 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S93 F93 Biomuta DOID:4159 / skin cancer [ cosmic ]
S93 C93 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T138 I138 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S284 F284 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S284 A284 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T369 A369 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T437 N437 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y574 H574 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
Y646 * Biomuta DOID:4159 / skin cancer [ cosmic ]
Y646 C646 Biomuta [ cosmic ]
S724 N724 Biomuta DOID:1319 / brain cancer [ cosmic ]
T725 N725 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]