iPTMnet Report for P32245 (MC4R)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P32245 / MC4R_HUMAN
Protein Name Melanocortin receptor 4
Gene Name Name: MC4R
Organism Homo sapiens (Human)

PRO ID PR:P32245
DAG View
PRO Name melanocortin receptor 4 (human)
Definition A melanocortin receptor 4 that is encoded in the genome of human.
Short Label hMC4R
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P32245 (MC4R) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y35 Phosphorylation PhosphoSitePlus
S36 Phosphorylation PhosphoSitePlus
Y41 Phosphorylation PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
Y148 Phosphorylation PhosphoSitePlus
Y157 Phosphorylation PhosphoSitePlus
C293 Methylation IEDB 31844290
T312 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   Signor 12639913
T312 Phosphorylation A0A0S2Z3I6 (ADRBK1) HPRD 12639913
T312 Phosphorylation P17612 (PRKACA) HPRD   PhosphoSitePlus   Signor 12639913
T312 Phosphorylation P25098 (GRK2) Signor 12639913
S329 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   Signor 12639913
S329 Phosphorylation A0A0S2Z3I6 (ADRBK1) HPRD 12639913
S329 Phosphorylation P17612 (PRKACA) HPRD   Signor 12639913
S329 Phosphorylation P25098 (GRK2) Signor 12639913
S330 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   Signor 12639913
S330 Phosphorylation A0A0S2Z3I6 (ADRBK1) HPRD 12639913
S330 Phosphorylation P17612 (PRKACA) HPRD 12639913
S330 Phosphorylation P25098 (GRK2) Signor 12639913


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S330 G330 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]