iPTMnet Report P31994 FCGR2B

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P31994 / FCG2B_HUMAN
Protein Name	Low affinity immunoglobulin gamma Fc region receptor II-b precursor
Gene Name	Name: FCGR2B Synonyms:CD32,FCG2,IGFR2;
Organism	Homo sapiens (Human)

PRO ID	PR:P31994 DAG View
PRO Name	low affinity immunoglobulin gamma Fc region receptor II-b (human)
Definition	A low affinity immunoglobulin gamma Fc region receptor II-b that is encoded in the genome of human.
Short Label	hFCGR2B
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P31994 (FCGR2B) as Substrate

Condensed View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	N180	N-Glycosylation		score1	GlyGen	24190977
	N187	N-Glycosylation		score1	GlyGen	24190977
	N199	N-Glycosylation		score1	GlyGen	24190977
	Y292	Phosphorylation		score4	IntAct neXtProt phospho.ELM PhosphoSitePlus RLIMS-P UniProt	8756631, 33409482, 10382761, ...8577729, 9603468, 10704309, 9148918
	Y292	Phosphorylation	P06241 (FYN)	score2	PhosphoSitePlus	10704309
	Y292	Phosphorylation	P07948 (LYN)	score3	phospho.ELM PhosphoSitePlus	8756631
	Y292	Phosphorylation	P51451 (BLK)	score3	neXtProt phospho.ELM PhosphoSitePlus	8756631
	S293	Phosphorylation		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	Y292	Phosphorylation		score1	HPRD	8756631
	Y292	Phosphorylation	P07948 (LYN)	score1	HPRD	8756631
	Y292	Phosphorylation	P51451 (BLK)	score1	HPRD	8756631
	S293	Phosphorylation		score0	HPRD	20166139

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S253	Phosphorylation		score1	PhosphoSitePlus
	Y273	Phosphorylation		score3	HPRD PhosphoSitePlus	8756631
	Y273	Phosphorylation	P07948 (LYN)	score1	HPRD	8756631
	Y273	Phosphorylation	P51451 (BLK)	score1	HPRD	8756631
	S274	Phosphorylation		score0	HPRD	20166139

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	Y291	Phosphorylation		score1	HPRD	8756631
	Y291	Phosphorylation	P07948 (LYN)	score1	HPRD	8756631
	Y291	Phosphorylation	P51451 (BLK)	score1	HPRD	8756631
	S292	Phosphorylation		score0	HPRD	20166139

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	Y272	Phosphorylation		score1	HPRD	8756631
	Y272	Phosphorylation	P07948 (LYN)	score1	HPRD	8756631
	Y272	Phosphorylation	P51451 (BLK)	score1	HPRD	8756631
	S273	Phosphorylation		score0	HPRD	20166139

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
N187	S187	Biomuta		DOID:10534 / stomach cancer [ icgc ]