iPTMnet Report for P30519 (HMOX2)
Protein Information
UniProt AC / UniProt ID | P30519 / HMOX2_HUMAN |
Protein Name | Heme oxygenase 2 |
Gene Name | Name: HMOX2 Synonyms:HO2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P30519 |
PRO Name | heme oxygenase 2 (human) |
Definition | A heme oxygenase 2 that is encoded in the genome of human. |
Short Label | hHMOX2 |
Category | organism-gene |
P30519 (HMOX2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Acetylation | score1 | UniProt | 19413330, 25944712 | ||
S2 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S8 | Phosphorylation | score1 | PhosphoSitePlus | |||
S14 | Phosphorylation | score1 | PhosphoSitePlus | |||
K24 | Ubiquitination | score1 | PhosphoSitePlus | |||
S34 | Phosphorylation | score1 | PhosphoSitePlus | |||
K38 | Ubiquitination | score1 | PhosphoSitePlus | |||
K55 | Ubiquitination | score1 | PhosphoSitePlus | |||
K59 | Ubiquitination | score1 | PhosphoSitePlus | |||
C127 | Methylation | score1 | IEDB | 31844290 | ||
Y157 | Phosphorylation | score1 | PhosphoSitePlus | |||
K176 | Ubiquitination | score1 | PhosphoSitePlus | |||
K199 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y202 | Phosphorylation | score1 | PhosphoSitePlus | |||
K216 | Acetylation | score1 | PhosphoSitePlus | |||
S242 | O-Glycosylation | score1 | GlyGen | 34019948, 34229054, 29351928 | ||
T243 | O-Glycosylation | score1 | GlyGen | 34019948, 34229054, 29351928 | ||
K259 | Ubiquitination | score1 | PhosphoSitePlus | |||
K264 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y268 | Phosphorylation | score1 | PhosphoSitePlus | |||
S280 | Phosphorylation | score1 | PhosphoSitePlus | |||
C282 | S-Nitrosylation | score0 | dbSNO | 22178444 | ||
T286 | Phosphorylation | score1 | PhosphoSitePlus | |||
S295 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y314 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y315 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K38 | N38 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K59 | E59 | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
S79 | * | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
Y202 | C202 | Biomuta | DOID:5041 / esophageal cancer [ cosmic, icgc ] |