iPTMnet Report for P30405 (PPIF)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P30405 / PPIF_HUMAN
Protein Name Peptidyl-prolyl cis-trans isomerase F, mitochondrial precursor
Gene Name Name: PPIF
Synonyms:CYP3;
Organism Homo sapiens (Human)

PRO ID PR:P30405
DAG View
PRO Name peptidyl-prolyl cis-trans isomerase F, mitochondrial (human)
Definition A peptidyl-prolyl cis-trans isomerase F, mitochondrial that is encoded in the genome of human.
Short Label hPPIF
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P30405 (PPIF) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S31 Phosphorylation P31751 (AKT2) PhosphoSitePlus 25650317
S34 Phosphorylation PhosphoSitePlus
K57 Acetylation PhosphoSitePlus
K67 Acetylation PhosphoSitePlus
K73 Acetylation PhosphoSitePlus
K73 Sumoylation PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
K86 Acetylation PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
Y90 Phosphorylation PhosphoSitePlus
K91 Acetylation PhosphoSitePlus
S123 Phosphorylation PhosphoSitePlus
K167 Acetylation PhosphoSitePlus
K175 Acetylation PhosphoSitePlus
K182 Acetylation PhosphoSitePlus
K183 Acetylation PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus
S189 Phosphorylation PhosphoSitePlus
K190 Methylation PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
S191 Phosphorylation P49841 (GSK3B) PhosphoSitePlus   Signor 32814770
C203 S-Nitrosylation dbSNO 26338901


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S123 C123 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S186 F186 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K190 R190 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K190 E190 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]