Protein Information

Cytoscape View


UniProt AC / UniProt ID P29120 / NEC1_HUMAN
Protein Name Neuroendocrine convertase 1 precursor
Gene Name Name: PCSK1
Synonyms:NEC1;
Organism Homo sapiens (Human)

PRO ID PR:P29120
DAG View
PRO Name neuroendocrine convertase 1 (human)
Definition A neuroendocrine convertase 1 that is encoded in the genome of human.
Short Label hPCSK1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P29120 (PCSK1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T87 Phosphorylation PhosphoSitePlus
T632 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 23584533, 23234360
T640 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S643 O-Glycosylation GlyGen   PhosphoSitePlus 23584533


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T87 S87 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S643 F643 Biomuta DOID:4159 / skin cancer [ cosmic ]