iPTMnet Report for P29084 (GTF2E2)
Protein Information
UniProt AC / UniProt ID | P29084 / T2EB_HUMAN |
Protein Name | Transcription initiation factor IIE subunit beta |
Gene Name | Name: GTF2E2 Synonyms:TF2E2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P29084 |
PRO Name | transcription initiation factor IIE subunit beta (human) |
Definition | A transcription initiation factor IIE subunit beta that is encoded in the genome of human. |
Short Label | hGTF2E2 |
Category | organism-gene |
P29084 (GTF2E2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 22814378 | ||
S4 | Phosphorylation | score1 | PhosphoSitePlus | |||
S18 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18212344 | ||
T19 | Phosphorylation | score1 | PhosphoSitePlus | |||
K24 | Acetylation | score1 | PhosphoSitePlus | |||
S26 | Phosphorylation | score1 | PhosphoSitePlus | |||
S29 | Phosphorylation | score0 | HPRD | 20068231 | ||
S35 | Phosphorylation | score1 | PhosphoSitePlus | |||
S36 | Phosphorylation | score1 | PhosphoSitePlus | |||
K52 | Acetylation | score1 | PhosphoSitePlus | |||
S58 | Phosphorylation | score1 | PhosphoSitePlus | |||
S61 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K86 | Ubiquitination | score1 | PhosphoSitePlus | |||
T87 | Phosphorylation | score1 | PhosphoSitePlus | |||
K114 | Ubiquitination | score1 | PhosphoSitePlus | |||
K116 | Acetylation | score1 | PhosphoSitePlus | |||
T121 | Phosphorylation | score1 | PhosphoSitePlus | |||
K129 | Acetylation | score1 | PhosphoSitePlus | |||
K180 | Ubiquitination | score1 | PhosphoSitePlus | |||
K183 | Ubiquitination | score1 | PhosphoSitePlus | |||
K198 | Acetylation | score1 | PhosphoSitePlus | |||
K206 | Acetylation | score1 | PhosphoSitePlus | |||
K218 | Ubiquitination | score1 | PhosphoSitePlus | |||
S227 | Phosphorylation | score1 | PhosphoSitePlus | |||
K238 | Methylation | score1 | PhosphoSitePlus | |||
K238 | Ubiquitination | score1 | PhosphoSitePlus | |||
S264 | Phosphorylation | score1 | PhosphoSitePlus | |||
K271 | Ubiquitination | score1 | PhosphoSitePlus | |||
K282 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y284 | Phosphorylation | score1 | PhosphoSitePlus | |||
S285 | O-Glycosylation | score1 | GlyGen | 28510447, 36580660, 31373491 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K86 | N86 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
T87 | A87 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
T121 | I121 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K129 | N129 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K129 | R129 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
K183 | E183 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K198 | N198 | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
S227 | F227 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K282 | N282 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] |