iPTMnet Report P28300 LOX

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P28300 / LYOX_HUMAN
Protein Name	Protein-lysine 6-oxidase precursor
Gene Name	Name: LOX
Organism	Homo sapiens (Human)

PRO ID	PR:P28300 DAG View
PRO Name	protein-lysine 6-oxidase (human)
Definition	A protein-lysine 6-oxidase that is encoded in the genome of human.
Short Label	hLOX
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P28300 (LOX) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	N81	N-Glycosylation		score1	GlyGen	23090970, 29741879, 30237853, ...29391424, 24190977
	T89	O-Glycosylation		score2	GlyGen PhosphoSitePlus	23584533, 30459171
	N97	N-Glycosylation		score1	GlyGen	23345538
	T113	O-Glycosylation		score2	GlyGen PhosphoSitePlus	23584533
	T120	O-Glycosylation		score2	GlyGen PhosphoSitePlus	23584533
	Y129	O-Glycosylation		score1	GlyGen	23584533, 25813380
	S130	O-Glycosylation		score2	GlyGen PhosphoSitePlus	23584533
	T131	O-Glycosylation		score2	GlyGen PhosphoSitePlus	23584533
	S132	O-Glycosylation		score2	GlyGen PhosphoSitePlus	23584533
	N144	N-Glycosylation		score1	GlyGen	23090970, 23345538, 30237853, ...29391424, 24190977
	T146	O-Glycosylation		score1	GlyGen	30459171, 35254053
	N381	N-Glycosylation		score1	GlyGen	29391424
	Y384	Phosphorylation		score1	PhosphoSitePlus
	T413	O-Glycosylation		score2	GlyGen PhosphoSitePlus	23584533

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	N97	N-Glycosylation		score1	PRO	23345538
	N144	N-Glycosylation		score1	PRO	23345538

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
T113	I113	Biomuta		DOID:10283 / prostate cancer [ cosmic ]
T146	A146	Biomuta		DOID:8618 / oral cavity cancer [ cosmic ]