iPTMnet Report for P28223 (HTR2A)
Protein Information
UniProt AC / UniProt ID | P28223 / 5HT2A_HUMAN |
Protein Name | 5-hydroxytryptamine receptor 2A |
Gene Name | Name: HTR2A Synonyms:HTR2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P28223 |
PRO Name | 5-hydroxytryptamine receptor 2A (human) |
Definition | A 5-hydroxytryptamine receptor 2A that is encoded in the genome of human. |
Short Label | hHTR2A |
Category | organism-gene |
P28223 (HTR2A) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S280 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 24637012 | ||
S287 | Phosphorylation | score1 | PhosphoSitePlus | |||
S288 | Phosphorylation | score1 | PhosphoSitePlus | |||
S290 | Phosphorylation | score1 | PhosphoSitePlus | |||
S291 | Phosphorylation | score1 | PhosphoSitePlus | |||
S298 | Phosphorylation | score1 | PhosphoSitePlus | |||
S305 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y419 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S280 | Y280 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S288 | C288 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S288 | P288 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S288 | Y288 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S298 | L298 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |