iPTMnet Report for P28072 (PSMB6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P28072 / PSB6_HUMAN
Protein Name Proteasome subunit beta type-6 precursor
Gene Name Name: PSMB6
Synonyms:LMPY,Y;
Organism Homo sapiens (Human)

PRO ID PR:P28072
DAG View
PRO Name proteasome subunit beta type-6 (human)
Definition A proteasome subunit beta type-6 that is encoded in the genome of human.
Short Label hPSMB6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P28072 (PSMB6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
R9 Methylation PhosphoSitePlus
T23 Phosphorylation PhosphoSitePlus
T54 Phosphorylation PhosphoSitePlus
T56 Phosphorylation PhosphoSitePlus
S58 Phosphorylation PhosphoSitePlus
Y59 Phosphorylation PhosphoSitePlus
R63 Methylation PhosphoSitePlus
K67 Acetylation PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
T69 Phosphorylation PhosphoSitePlus   UniProt 23186163
R74 Methylation PhosphoSitePlus
K118 Acetylation PhosphoSitePlus
S158 Phosphorylation PhosphoSitePlus
Y177 Phosphorylation PhosphoSitePlus
K183 Ubiquitination PhosphoSitePlus
C186 Methylation IEDB 31844290
T190 Phosphorylation PhosphoSitePlus
S203 Phosphorylation PhosphoSitePlus
S204 Phosphorylation PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R9 L9 Biomuta DOID:1612 / breast cancer [ icgc ]
S58 P58 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R63 Q63 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R63 G63 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K67 E67 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K118 N118 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S203 Y203 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]