Protein Information

Cytoscape View


UniProt AC / UniProt ID P27918 / PROP_HUMAN
Protein Name Properdin precursor
Gene Name Name: CFP
Synonyms:PFC;
Organism Homo sapiens (Human)

PRO ID PR:P27918
DAG View
PRO Name properdin (human)
Definition A properdin that is encoded in the genome of human.
Short Label hCFP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P27918 (CFP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S39 Phosphorylation PhosphoSitePlus
S40 Phosphorylation PhosphoSitePlus
W83 C-Glycosylation GlyGen   UniProt 31507604, 10878002
W86 C-Glycosylation GlyGen   UniProt 31507604, 10878002
T92 O-Glycosylation GlyGen   UniProt 12096136, 31507604
W139 C-Glycosylation GlyGen   UniProt 31507604, 10878002
W142 C-Glycosylation GlyGen   UniProt 31507604, 10878002
W145 C-Glycosylation GlyGen   UniProt 31507604, 10878002
T151 O-Glycosylation GlyGen   UniProt 12096136, 31507604
W196 C-Glycosylation GlyGen   UniProt 31507604, 10878002
W199 C-Glycosylation GlyGen   UniProt 31507604, 10878002
W202 C-Glycosylation GlyGen   UniProt 31507604
S208 O-Glycosylation GlyGen   UniProt 12096136, 31507604
W260 C-Glycosylation GlyGen   UniProt 31507604, 10878002
W263 C-Glycosylation GlyGen   UniProt 31507604, 10878002
T272 O-Glycosylation GlyGen   UniProt 12096136, 31507604
W321 C-Glycosylation GlyGen   UniProt 31507604, 10878002
W324 C-Glycosylation GlyGen   UniProt 31507604, 10878002
W382 C-Glycosylation GlyGen   UniProt 31507604, 10878002
W385 C-Glycosylation GlyGen   UniProt 31507604, 10878002
W388 C-Glycosylation GlyGen   UniProt 31507604, 10878002
N428 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 19139490


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
W86 R86 Biomuta DOID:3571 / liver cancer [ cosmic ]
T92 M92 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ]
W142 C142 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
W142 L142 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
T151 I151 Biomuta DOID:263 / kidney cancer [ cosmic ]
W321 R321 Biomuta DOID:1324 / lung cancer [ cosmic ]