iPTMnet Report for P26641 (EEF1G)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P26641 / EF1G_HUMAN
Protein Name Elongation factor 1-gamma
Gene Name Name: EEF1G
Synonyms:EF1G;ORFNames:PRO1608;
Organism Homo sapiens (Human)

PRO ID PR:P26641
DAG View
PRO Name elongation factor 1-gamma (human)
Definition An elongation factor 1-gamma that is encoded in the genome of human.
Short Label hEEF1G
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P26641 (EEF1G) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 22223895
K17 Methylation PhosphoSitePlus
K17 Ubiquitination PhosphoSitePlus
Y24 Phosphorylation PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus
S33 Phosphorylation PhosphoSitePlus
T43 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
T46 Phosphorylation PhosphoSitePlus
R51 Methylation PhosphoSitePlus
K52 Acetylation PhosphoSitePlus
K132 Acetylation PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
Y145 Phosphorylation PhosphoSitePlus
K147 Acetylation PhosphoSitePlus   UniProt 19608861
K147 Ubiquitination PhosphoSitePlus
R149 Methylation PhosphoSitePlus
C194 S-Nitrosylation dbSNO 26338901, 22178444, 19366988, ...18335467
K208 Acetylation PhosphoSitePlus
K208 Ubiquitination PhosphoSitePlus
C210 Methylation IEDB 31844290
K212 Acetylation PhosphoSitePlus
K212 Ubiquitination PhosphoSitePlus
K219 Acetylation PhosphoSitePlus
K219 Ubiquitination PhosphoSitePlus
K220 Acetylation PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
T230 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
K253 Sumoylation PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
C266 S-Nitrosylation dbSNO 26338901
K275 Ubiquitination PhosphoSitePlus
K277 Ubiquitination PhosphoSitePlus
K285 Acetylation PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
K294 Acetylation PhosphoSitePlus
K294 Ubiquitination PhosphoSitePlus
K296 Acetylation PhosphoSitePlus
S298 Phosphorylation PhosphoSitePlus
S387 Phosphorylation PhosphoSitePlus
K401 Acetylation PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
S406 Phosphorylation PhosphoSitePlus
Y416 Phosphorylation PhosphoSitePlus
S418 Phosphorylation PhosphoSitePlus
K428 Acetylation PhosphoSitePlus
K434 Acetylation PhosphoSitePlus   UniProt 19608861
K434 Ubiquitination PhosphoSitePlus
K437 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T43 Phosphorylation HPRD 19651622, 17081983
T46 Phosphorylation HPRD 19651622, 18669648, 20058876, ...20068231
T230 Phosphorylation HPRD 20068231
S286 Phosphorylation HPRD 20068231
S406 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y24 N24 Biomuta DOID:363 / uterine cancer [ cosmic ]
S33 C33 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R51 C51 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
K253 R253 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K294 N294 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y416 H416 Biomuta DOID:363 / uterine cancer [ icgc ]
S418 F418 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K437 E437 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]