iPTMnet Report for P25787 (PSMA2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P25787 / PSA2_HUMAN
Protein Name Proteasome subunit alpha type-2
Gene Name Name: PSMA2
Synonyms:HC3,PSC3;
Organism Homo sapiens (Human)

PRO ID PR:P25787
DAG View
PRO Name proteasome subunit alpha type-2 (human)
Definition A proteasome subunit alpha type-2 that is encoded in the genome of human.
Short Label hPSMA2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P25787 (PSMA2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
Y6 Phosphorylation PhosphoSitePlus
S7 Phosphorylation PhosphoSitePlus   UniProt 23186163
S9 Phosphorylation PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus   UniProt 23186163
S16 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y24 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 15592455
S35 Phosphorylation PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
K50 Acetylation PhosphoSitePlus
K50 Ubiquitination PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
K53 Acetylation PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
Y57 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18083107, 20068231
K64 Sumoylation PhosphoSitePlus
K64 Ubiquitination PhosphoSitePlus
K70 Acetylation PhosphoSitePlus   UniProt 19608861
K70 Ubiquitination PhosphoSitePlus
Y76 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18083107, 23186163
S77 Phosphorylation PhosphoSitePlus
K92 Acetylation PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
Y97 Phosphorylation PhosphoSitePlus
Y98 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 15592455
Y101 Phosphorylation PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
Y167 Phosphorylation PhosphoSitePlus
K171 Acetylation PhosphoSitePlus   UniProt 19608861
K171 Ubiquitination PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
T190 Phosphorylation PhosphoSitePlus
C213 Methylation IEDB 31844290
T222 Phosphorylation PhosphoSitePlus
T224 Phosphorylation PhosphoSitePlus
K227 Acetylation PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 V2 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S35 F35 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y76 H76 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K165 N165 Biomuta DOID:363 / uterine cancer [ icgc ]
K165 Q165 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T190 I190 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K227 R227 Biomuta DOID:1324 / lung cancer [ cosmic ]