iPTMnet Report for P25398 (RPS12)
Protein Information
UniProt AC / UniProt ID | P25398 / RS12_HUMAN |
Protein Name | Small ribosomal subunit protein eS12 |
Gene Name | Name: RPS12 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P25398 |
PRO Name | 40S ribosomal protein S12 (human) |
Definition | A 40S ribosomal protein S12 that is encoded in the genome of human. |
Short Label | hRPS12 |
Category | organism-gene |
P25398 (RPS12) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 19413330, 20068231, 22814378, ... | ||
K23 | Ubiquitination | score1 | PhosphoSitePlus | |||
T24 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
R33 | Methylation | score1 | PhosphoSitePlus | |||
K40 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y61 | Phosphorylation | score1 | PhosphoSitePlus | |||
K78 | Ubiquitination | score1 | PhosphoSitePlus | |||
K84 | Acetylation | score1 | PhosphoSitePlus | |||
K84 | Ubiquitination | score1 | PhosphoSitePlus | |||
C92 | Methylation | score1 | IEDB | 31844290 | ||
C92 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
K93 | Ubiquitination | score1 | PhosphoSitePlus | |||
K99 | Acetylation | score1 | PhosphoSitePlus | |||
K102 | Ubiquitination | score1 | PhosphoSitePlus | |||
S107 | O-Glycosylation | score1 | GlyGen | 23301498, 33214551, 35138101, ... | ||
S107 | Phosphorylation | score1 | PhosphoSitePlus | |||
K112 | Acetylation | score1 | PhosphoSitePlus | |||
K112 | Ubiquitination | score1 | PhosphoSitePlus | |||
K116 | Acetylation | score1 | PhosphoSitePlus | |||
K116 | Ubiquitination | score1 | PhosphoSitePlus | |||
S118 | Phosphorylation | score1 | PhosphoSitePlus | |||
K121 | Acetylation | score1 | PhosphoSitePlus | |||
K121 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y127 | Phosphorylation | score1 | PhosphoSitePlus | |||
K129 | Acetylation | score1 | PhosphoSitePlus | |||
K129 | Methylation | score1 | PhosphoSitePlus | |||
K129 | Ubiquitination | score1 | PhosphoSitePlus | |||
K131 | Ubiquitination | score1 | PhosphoSitePlus | |||
K132 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y61 | C61 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
Y61 | F61 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
K84 | T84 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
K99 | N99 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S118 | Y118 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
K121 | N121 | Biomuta | DOID:2531 / hematologic cancer [ cosmic, icgc ] |