iPTMnet Report for P25024 (CXCR1)
Protein Information
UniProt AC / UniProt ID | P25024 / CXCR1_HUMAN |
Protein Name | C-X-C chemokine receptor type 1 |
Gene Name | Name: CXCR1 Synonyms:CMKAR1,IL8RA; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P25024 |
PRO Name | C-X-C chemokine receptor type 1 (human) |
Definition | A C-X-C chemokine receptor type 1 that is encoded in the genome of human. |
Short Label | hCXCR1 |
Category | organism-gene |
P25024 (CXCR1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
R279 | Methylation | score1 | PhosphoSitePlus | |||
R280 | Methylation | score1 | PhosphoSitePlus | |||
T290 | O-Glycosylation | score1 | GlyGen | 34105348 | ||
S298 | O-Glycosylation | score1 | GlyGen | 34105348 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R279 | C279 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ] | |
R279 | H279 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
R280 | H280 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
R280 | C280 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic, icgc ] |