iPTMnet Report for P24844 (MYL9)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P24844 / MYL9_HUMAN
Protein Name Myosin regulatory light polypeptide 9
Gene Name Name: MYL9
Synonyms:MLC2,MRLC1,MYRL2;
Organism Homo sapiens (Human)

PRO ID PR:P24844
DAG View
PRO Name myosin regulatory light polypeptide 9 (human)
Definition A myosin regulatory light polypeptide 9 that is encoded in the genome of human.
Short Label hMYL9
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P24844 (MYL9) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation P17252 (PRKCA) PhosphoSitePlus   Signor 22136066, 12802051, 18835557
S3 Phosphorylation P17252 (PRKCA) PhosphoSitePlus   Signor 22136066, 12802051, 18835557
T10 Phosphorylation P17252 (PRKCA) PhosphoSitePlus   Signor 22136066, 12802051, 18835557
T11 Phosphorylation PhosphoSitePlus
T19 Phosphorylation O43293 (DAPK3) , O75116 (ROCK2) , O14578 (CIT) , Q15746 (MYLK) , Q5VT25 (CDC42BPA) , Q13464 (ROCK1) IEDB   neXtProt   phospho.ELM   PRO   PhosphoSitePlus   Signor   UniProt 11942626, 2526655, 21457715, ...26169356, 12802051, 18854160, 27920218, 18669648, 18835557, 19851336, 8702756, 15096528, 15723050
S20 Phosphorylation O43293 (DAPK3) , O75116 (ROCK2) , Q14012 (CAMK1) , Q15746 (MYLK) , Q13153 (PAK1) , Q13177 (PAK2) , Q9Y5S2 (CDC42BPB) , Q5VT25 (CDC42BPA) , O14578 (CIT) , Q13464 (ROCK1) IntAct   neXtProt   phospho.ELM   PRO   PhosphoSitePlus   Signor   UniProt 11942626, 10047984, 21457715, ...2526655, 20956536, 10356987, 26169356, 21072057, 18854160, 12802051, 12081505, 18669648, 17015463, 19851336, 8702756, 10947843, 18835557, 15723050, 3839510, 21408167
S29 Phosphorylation PhosphoSitePlus
K35 Acetylation PhosphoSitePlus
K51 Acetylation PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
T97 Phosphorylation PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus
T128 Phosphorylation PhosphoSitePlus
T135 Phosphorylation PhosphoSitePlus
Y143 Phosphorylation P00533 (EGFR) phospho.ELM   PhosphoSitePlus 8578591
K150 Ubiquitination PhosphoSitePlus
K151 Sumoylation PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
Y156 Phosphorylation P00533 (EGFR) phospho.ELM   PhosphoSitePlus 8578591
K164 Ubiquitination PhosphoSitePlus
K168 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T19 Phosphorylation HPRD 19562805, 20166139, 18669648, ...19664995, 20068231
S20 Phosphorylation HPRD 20166139, 18669648, 18491316, ...20068231, 18707149
Site PTM Type PTM Enzyme Score Source PMID
T19 Phosphorylation HPRD 19562805, 20166139, 18669648, ...19664995, 20068231
S20 Phosphorylation HPRD 20166139, 18669648, 18491316, ...20068231, 18707149


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048505 (hMYL9/InitMet-/Phos:1) pS20 PRO
PR:000048506 (hMYL9/InitMet-/Phos:2) pT19 PRO
PR:000048507 (hMYL9/InitMet-/Phos:3) pT19,pS20 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S2 Y2 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T11 I11 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ]
T11 S11 Biomuta DOID:363 / uterine cancer [ icgc ]
S60 L60 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S60 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K168 * Biomuta DOID:4159 / skin cancer [ cosmic ]