iPTMnet Report for P24394 (IL4R)
Protein Information
UniProt AC / UniProt ID | P24394 / IL4RA_HUMAN |
Protein Name | Interleukin-4 receptor subunit alpha precursor |
Gene Name | Name: IL4R Synonyms:IL4RA;ORFNames:582J2.1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P24394 |
PRO Name | interleukin-4 receptor subunit alpha (human) |
Definition | An interleukin-4 receptor subunit alpha that is encoded in the genome of human. |
Short Label | hIL4R |
Category | organism-gene |
P24394 (IL4R) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
N53 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
N176 | N-Glycosylation | score1 | GlyGen | 29671580, 24190977 | ||
K192 | Ubiquitination | score1 | PhosphoSitePlus | |||
S383 | Phosphorylation | score1 | PhosphoSitePlus | |||
S387 | Phosphorylation | score1 | PhosphoSitePlus | |||
S390 | Phosphorylation | score1 | PhosphoSitePlus | |||
S391 | Phosphorylation | score1 | PhosphoSitePlus | |||
S470 | Phosphorylation | score1 | PhosphoSitePlus | |||
S474 | Phosphorylation | score1 | PhosphoSitePlus | |||
T476 | Phosphorylation | score1 | PhosphoSitePlus | |||
T487 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y497 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus UniProt | 8124718, 9545332, 9697832 | ||
Y575 | Phosphorylation | score4 | IntAct phospho.ELM PhosphoSitePlus UniProt | 8624803, 9392697, 10358772 | ||
Y603 | Phosphorylation | score4 | IntAct phospho.ELM UniProt | 8624803, 9392697, 10358772, ... | ||
S616 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y631 | Phosphorylation | score4 | IntAct phospho.ELM UniProt | 8624803, 8816495, 9651359, ... | ||
Y713 | Phosphorylation | score4 | IntAct phospho.ELM PhosphoSitePlus | 9670964, 11714803 | ||
S753 | Phosphorylation | score1 | PhosphoSitePlus | |||
T756 | Phosphorylation | score1 | PhosphoSitePlus | |||
S791 | Phosphorylation | score1 | PhosphoSitePlus | |||
T820 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y821 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
N176 | S176 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
S387 | L387 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T487 | M487 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y603 | C603 | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
Y713 | H713 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S753 | L753 | Biomuta | [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
Y821 | C821 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |