iPTMnet Report for P24043 (LAMA2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P24043 / LAMA2_HUMAN
Protein Name Laminin subunit alpha-2 precursor
Gene Name Name: LAMA2
Synonyms:LAMM;
Organism Homo sapiens (Human)

PRO ID PR:P24043
DAG View
PRO Name laminin subunit alpha-2 (human)
Definition A laminin subunit alpha-2 that is encoded in the genome of human.
Short Label hLAMA2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P24043 (LAMA2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N55 N-Glycosylation GlyGen 29741879
N89 N-Glycosylation GlyGen 23090970, 29391424
C176 Methylation IEDB 31844290
Y274 Phosphorylation PhosphoSitePlus
Y275 Phosphorylation PhosphoSitePlus
N303 N-Glycosylation GlyGen 29741879
N363 N-Glycosylation GlyGen   UniProt 16335952, 29391424
N470 N-Glycosylation GlyGen 29391424
Y897 Phosphorylation PhosphoSitePlus
Y905 Phosphorylation PhosphoSitePlus
Y1249 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 16212419
Y1258 Phosphorylation PhosphoSitePlus
Y1270 Phosphorylation PhosphoSitePlus
S1358 Phosphorylation HPRD   PhosphoSitePlus 19664995
T1369 Phosphorylation HPRD   PhosphoSitePlus 19664995
N1597 N-Glycosylation GlyGen 29391424
N1614 N-Glycosylation GlyGen 29391424
K1676 Acetylation PhosphoSitePlus
K1683 Acetylation PhosphoSitePlus
N1700 N-Glycosylation GlyGen 29391424
N1810 N-Glycosylation GlyGen 29391424
N1901 N-Glycosylation GlyGen   UniProt 19159218
N1916 N-Glycosylation GlyGen   UniProt 29391424, 19159218
N1920 N-Glycosylation GlyGen   UniProt 19159218
K1943 Methylation PhosphoSitePlus
N2017 N-Glycosylation GlyGen   UniProt 29391424, 19159218
N2028 N-Glycosylation GlyGen 29741879, 29391424
N2045 N-Glycosylation GlyGen 29391424
N2126 N-Glycosylation GlyGen 29741879, 29391424
S2205 Phosphorylation PhosphoSitePlus
S2212 Phosphorylation PhosphoSitePlus
N2240 N-Glycosylation GlyGen 29391424
N2360 N-Glycosylation GlyGen 29391424
N2478 N-Glycosylation GlyGen 29391424
Y2514 Phosphorylation PhosphoSitePlus
N2558 N-Glycosylation GlyGen 29391424
S2567 Phosphorylation PhosphoSitePlus
T2581 Phosphorylation PhosphoSitePlus
N2648 N-Glycosylation GlyGen   UniProt 29391424, 19159218
K2658 Ubiquitination PhosphoSitePlus
S2691 Phosphorylation PhosphoSitePlus
T2741 O-Glycosylation GlyGen 30459171
T2743 O-Glycosylation GlyGen 30459171
T2747 O-Glycosylation GlyGen 30459171
S2772 Phosphorylation PhosphoSitePlus
T2781 Phosphorylation PhosphoSitePlus
K2856 Ubiquitination PhosphoSitePlus
Y2886 Phosphorylation PhosphoSitePlus
N2893 N-Glycosylation GlyGen 29391424
Y2894 Phosphorylation PhosphoSitePlus
T2974 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C176 Y176 Biomuta DOID:10534 / stomach cancer [ cosmic ]
N303 Y303 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
N303 K303 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T1369 A1369 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
N1810 S1810 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
N1810 Y1810 Biomuta DOID:1612 / breast cancer [ icgc ]
N1901 Y1901 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
N1916 D1916 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K1943 Q1943 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S2205 R2205 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S2691 Y2691 Biomuta DOID:4159 / skin cancer [ cosmic ]
T2741 M2741 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T2781 N2781 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K2856 N2856 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T2974 A2974 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]