iPTMnet Report for P23975 (SLC6A2)
Protein Information
UniProt AC / UniProt ID | P23975 / SC6A2_HUMAN |
Protein Name | Sodium-dependent noradrenaline transporter |
Gene Name | Name: SLC6A2 Synonyms:NAT1,NET1,SLC6A5; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P23975 |
PRO Name | sodium-dependent noradrenaline transporter (human) |
Definition | A sodium-dependent noradrenaline transporter that is encoded in the genome of human. |
Short Label | hSLC6A2 |
Category | organism-gene |
P23975 (SLC6A2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T30 | Phosphorylation | score1 | PhosphoSitePlus | |||
S194 | Phosphorylation | score1 | PhosphoSitePlus | |||
S203 | Phosphorylation | score1 | PhosphoSitePlus | |||
T258 | Phosphorylation | score1 | PhosphoSitePlus | |||
S259 | Phosphorylation | Q02156 (PRKCE) | score2 | PhosphoSitePlus | 16740633 | |
C351 | S-Nitrosylation | score2 | dbSNO | 22178444, 10882390 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S203 | F203 | Biomuta | DOID:9253 / gastrointestinal stromal tumor [ cosmic ] | |
S259 | L259 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
S259 | P259 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
C351 | Y351 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] |