iPTMnet Report for P23975 (SLC6A2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P23975 / SC6A2_HUMAN
Protein Name Sodium-dependent noradrenaline transporter
Gene Name Name: SLC6A2
Synonyms:NAT1,NET1,SLC6A5;
Organism Homo sapiens (Human)

PRO ID PR:P23975
DAG View
PRO Name sodium-dependent noradrenaline transporter (human)
Definition A sodium-dependent noradrenaline transporter that is encoded in the genome of human.
Short Label hSLC6A2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P23975 (SLC6A2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T30 Phosphorylation PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
S203 Phosphorylation PhosphoSitePlus
T258 Phosphorylation PhosphoSitePlus
S259 Phosphorylation Q02156 (PRKCE) PhosphoSitePlus 16740633
C351 S-Nitrosylation dbSNO 22178444, 10882390
Site PTM Type PTM Enzyme Score Source PMID
S194 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S203 F203 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
S259 L259 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S259 P259 Biomuta DOID:10534 / stomach cancer [ cosmic ]
C351 Y351 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]