Protein Information

Cytoscape View


UniProt AC / UniProt ID P23677 / IP3KA_HUMAN
Protein Name Inositol-trisphosphate 3-kinase A
Gene Name Name: ITPKA
Organism Homo sapiens (Human)

PRO ID PR:P23677
DAG View
PRO Name inositol-trisphosphate 3-kinase A (human)
Definition An inositol-trisphosphate 3-kinase A that is encoded in the genome of human.
Short Label hITPKA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P23677 (ITPKA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S20 Phosphorylation PhosphoSitePlus
R62 Methylation PhosphoSitePlus
S180 Phosphorylation PhosphoSitePlus
S197 Phosphorylation PhosphoSitePlus   UniProt 23186163
T311 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   Signor 9374536, 9155020
T311 Phosphorylation P17252 (PRKCA) HPRD 9374536, 9155020
T311 Phosphorylation P17612 (PRKACA) HPRD 9374536, 9155020
T311 Phosphorylation Q9UQM7 (CAMK2A) PhosphoSitePlus   Signor 9155020
S323 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T311 A311 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]