iPTMnet Report for P23470 (PTPRG)
Protein Information
UniProt AC / UniProt ID | P23470 / PTPRG_HUMAN |
Protein Name | Receptor-type tyrosine-protein phosphatase gamma precursor |
Gene Name | Name: PTPRG Synonyms:PTPG; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P23470 |
PRO Name | receptor-type tyrosine-protein phosphatase gamma (human) |
Definition | A receptor-type tyrosine-protein phosphatase gamma that is encoded in the genome of human. |
Short Label | hPTPRG |
Category | organism-gene |
P23470 (PTPRG) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
N109 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
N113 | N-Glycosylation | score2 | GlyGen UniProt | 16335952, 24190977 | ||
Y132 | Phosphorylation | score1 | PhosphoSitePlus | |||
N156 | N-Glycosylation | score1 | GlyGen | 23090970, 24190977 | ||
S320 | Phosphorylation | score1 | PhosphoSitePlus | |||
S325 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y419 | Phosphorylation | score1 | PhosphoSitePlus | |||
S433 | Phosphorylation | score1 | PhosphoSitePlus | |||
S436 | Phosphorylation | score1 | PhosphoSitePlus | |||
N444 | N-Glycosylation | score2 | GlyGen UniProt | 16335952, 23090970, 29391424, ... | ||
T514 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
S561 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
N619 | N-Glycosylation | score1 | GlyGen | 29391424 | ||
T633 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
T640 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 30459171 | ||
T649 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
T653 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
T656 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
T681 | Phosphorylation | score1 | PhosphoSitePlus | |||
T715 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
N722 | N-Glycosylation | score1 | GlyGen | 29391424 | ||
S782 | Phosphorylation | score1 | PhosphoSitePlus | |||
N813 | N-Glycosylation | score1 | GlyGen | 29391424 | ||
S815 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y880 | Phosphorylation | score1 | PhosphoSitePlus | |||
K902 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y906 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y911 | Phosphorylation | score1 | PhosphoSitePlus | |||
K929 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y1021 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1023 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1034 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1083 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1155 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y1164 | Phosphorylation | score1 | PhosphoSitePlus | |||
N1181 | N-Glycosylation | score1 | GlyGen | 29391424 | ||
S1182 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
K1201 | Acetylation | score1 | PhosphoSitePlus | |||
N1207 | N-Glycosylation | score1 | GlyGen | 29391424 | ||
Y1307 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1409 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1435 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
N109 | I109 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S433 | N433 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T514 | M514 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic, icgc ] | |
N813 | T813 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
Y880 | N880 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
Y880 | * | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
K929 | M929 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
Y1021 | H1021 | Biomuta | [ cosmic ] | |
Y1164 | H1164 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
N1207 | D1207 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] |