iPTMnet Report for P21730 (C5AR1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P21730 / C5AR1_HUMAN
Protein Name C5a anaphylatoxin chemotactic receptor 1
Gene Name Name: C5AR1
Synonyms:C5AR,C5R1;
Organism Homo sapiens (Human)

PRO ID PR:P21730
DAG View
PRO Name C5a anaphylatoxin chemotactic receptor 1 (human)
Definition A C5a anaphylatoxin chemotactic receptor 1 that is encoded in the genome of human.
Short Label hC5AR1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P21730 (C5AR1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y11 Phosphorylation PhosphoSitePlus
Y14 Phosphorylation PhosphoSitePlus
S314 Phosphorylation P17252 (PRKCA) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 7642584
S317 Phosphorylation P17252 (PRKCA) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 7642584, 10636859, 12464600
T324 Phosphorylation PhosphoSitePlus
S327 Phosphorylation P17252 (PRKCA) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 7642584, 10636859, 20058876, ...12464600
S332 Phosphorylation P17252 (PRKCA) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 7642584, 10636859
S334 Phosphorylation Q05655 (PRKCD) , P17252 (PRKCA) , P05129 (PRKCG) , P05771 (PRKCB) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 12464600, 10636859, 7642584, ...17145764
S338 Phosphorylation P17252 (PRKCA) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 12464600, 10636859, 7642584


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S314 F314 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S338 Y338 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]