iPTMnet Report for P21283 (ATP6V1C1)
Protein Information
UniProt AC / UniProt ID | P21283 / VATC1_HUMAN |
Protein Name | V-type proton ATPase subunit C 1 |
Gene Name | Name: ATP6V1C1 Synonyms:ATP6C,ATP6D,VATC; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P21283 |
PRO Name | V-type proton ATPase subunit C 1 (human) |
Definition | A V-type proton ATPase subunit C 1 that is encoded in the genome of human. |
Short Label | hATP6V1C1 |
Category | organism-gene |
P21283 (ATP6V1C1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T2 | Acetylation | score1 | UniProt | 22223895, 25944712 | ||
K21 | Ubiquitination | score1 | PhosphoSitePlus | |||
K28 | Ubiquitination | score1 | PhosphoSitePlus | |||
K37 | Acetylation | score1 | PhosphoSitePlus | |||
K127 | Ubiquitination | score1 | PhosphoSitePlus | |||
K137 | Ubiquitination | score1 | PhosphoSitePlus | |||
K147 | Ubiquitination | score1 | PhosphoSitePlus | |||
K156 | Ubiquitination | score1 | PhosphoSitePlus | |||
S165 | Phosphorylation | score1 | PhosphoSitePlus | |||
K171 | Ubiquitination | score1 | PhosphoSitePlus | |||
C225 | S-Nitrosylation | score0 | dbSNO | 19483679 | ||
K232 | Ubiquitination | score1 | PhosphoSitePlus | |||
K245 | Ubiquitination | score1 | PhosphoSitePlus | |||
S362 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18077418 | ||
Y367 | Phosphorylation | score1 | PhosphoSitePlus | |||
C376 | S-Nitrosylation | score0 | dbSNO | 19483679 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K156 | R156 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
K156 | N156 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
K245 | T245 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
Y367 | C367 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |