Protein Information

Cytoscape View


UniProt AC / UniProt ID P20794 / MAK_HUMAN
Protein Name Serine/threonine-protein kinase MAK
Gene Name Name: MAK
Organism Homo sapiens (Human)

PRO ID PR:P20794
DAG View
PRO Name serine/threonine-protein kinase MAK (human)
Definition A serine/threonine-protein kinase MAK that is encoded in the genome of human.
Short Label hMAK
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P20794 (MAK) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y156 Phosphorylation PhosphoSitePlus
T157 Phosphorylation PhosphoSitePlus   Signor   UniProt 21986944
T157 Phosphorylation P20794 (MAK) Signor   UniProt 21986944
Y159 Phosphorylation PhosphoSitePlus   Signor   UniProt 21986944
Y159 Phosphorylation P20794 (MAK) Signor   UniProt 21986944
S161 Phosphorylation PhosphoSitePlus
T162 Phosphorylation PhosphoSitePlus
S457 Phosphorylation PhosphoSitePlus
S476 Phosphorylation PhosphoSitePlus
Y480 Phosphorylation PhosphoSitePlus
S510 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T5 Phosphorylation HPRD 20068231


P20794 (MAK) as PTM Enzyme



Substrate Site Score Source PMID
P20794 (MAK) T157 Signor   UniProt 21986944
P20794 (MAK) Y159 Signor   UniProt 21986944


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S457 R457 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y480 C480 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]