iPTMnet Report for P20138 (CD33)
Protein Information
UniProt AC / UniProt ID | P20138 / CD33_HUMAN |
Protein Name | Myeloid cell surface antigen CD33 precursor |
Gene Name | Name: CD33 Synonyms:SIGLEC3; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P20138 |
PRO Name | myeloid cell surface antigen CD33 (human) |
Definition | A CD33 molecule that is encoded in the genome of human. |
Short Label | hCD33 |
Category | organism-gene |
P20138 (CD33) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T42 | Phosphorylation | score1 | IEDB | 32357974 | ||
K77 | Ubiquitination | score1 | PhosphoSitePlus | |||
N99 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
N100 | N-Glycosylation | score4 | GlyGen UniProt | 8702538, 24190977 | ||
N113 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
N209 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
T226 | Phosphorylation | score1 | PhosphoSitePlus | |||
T239 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
T239 | Phosphorylation | score1 | PhosphoSitePlus | |||
T240 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
S248 | Phosphorylation | score1 | PhosphoSitePlus | |||
K250 | Ubiquitination | score1 | PhosphoSitePlus | |||
T299 | Phosphorylation | score1 | PhosphoSitePlus | |||
T302 | Phosphorylation | score1 | PhosphoSitePlus | |||
S307 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y340 | Phosphorylation | P12931 (SRC) , P06239 (LCK) | score4 | IntAct phospho.ELM PhosphoSitePlus Signor UniProt | 10206955, 10887109, 10556798 | |
Y358 | Phosphorylation | score4 | IntAct phospho.ELM PhosphoSitePlus UniProt | 10206955, 10887109, 10556798 | ||
T363 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T42 | P42 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
N99 | S99 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
N99 | I99 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
N209 | Y209 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
T226 | I226 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S248 | L248 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T299 | N299 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
T299 | A299 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |