iPTMnet Report for P19971 (TYMP)
Protein Information
UniProt AC / UniProt ID | P19971 / TYPH_HUMAN |
Protein Name | Thymidine phosphorylase precursor |
Gene Name | Name: TYMP Synonyms:ECGF1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P19971 |
PRO Name | thymidine phosphorylase (human) |
Definition | A thymidine phosphorylase that is encoded in the genome of human. |
Short Label | hTYMP |
Category | organism-gene |
P19971 (TYMP) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T6 | Phosphorylation | score1 | PhosphoSitePlus | |||
S19 | Phosphorylation | score1 | PhosphoSitePlus | |||
S23 | Phosphorylation | score1 | PhosphoSitePlus | |||
S30 | Phosphorylation | score1 | PhosphoSitePlus | |||
S50 | Phosphorylation | score1 | PhosphoSitePlus | |||
T154 | Phosphorylation | score1 | PhosphoSitePlus | |||
T271 | Phosphorylation | score1 | PhosphoSitePlus | |||
K275 | Acetylation | score1 | PhosphoSitePlus | |||
S409 | Phosphorylation | score1 | PhosphoSitePlus | |||
T435 | Phosphorylation | score1 | PhosphoSitePlus | |||
S471 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K275 | E275 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S409 | I409 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S471 | L471 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, icgc ] DOID:1781 / thyroid cancer [ icgc ] |