iPTMnet Report for P19971 (TYMP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P19971 / TYPH_HUMAN
Protein Name Thymidine phosphorylase precursor
Gene Name Name: TYMP
Synonyms:ECGF1;
Organism Homo sapiens (Human)

PRO ID PR:P19971
DAG View
PRO Name thymidine phosphorylase (human)
Definition A thymidine phosphorylase that is encoded in the genome of human.
Short Label hTYMP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P19971 (TYMP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T6 Phosphorylation PhosphoSitePlus
S19 Phosphorylation PhosphoSitePlus
S23 Phosphorylation PhosphoSitePlus
S30 Phosphorylation PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus
T154 Phosphorylation PhosphoSitePlus
T271 Phosphorylation PhosphoSitePlus
K275 Acetylation PhosphoSitePlus
S409 Phosphorylation PhosphoSitePlus
T435 Phosphorylation PhosphoSitePlus
S471 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T271 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K275 E275 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S409 I409 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S471 L471 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, icgc ] DOID:1781 / thyroid cancer [ icgc ]